Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC160Coiled-coil domain containing 160. (327 aa)    
Predicted Functional Partners:
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 0.805
SQLE
Squalene epoxidase.
   
 0.764
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.712
LOC100673402
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.712
FAXDC2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
   
 0.712
LOC100673111
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.712
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.672
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.634
ERG28
Ergosterol biosynthesis 28 homolog.
   
 
 0.607
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.599
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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