ATF2 protein (Loxodonta africana) - STRING interaction network

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ATF2

Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)

Predicted Functional Partners:

MAPK14

0.990

JUN

0.989

MAPK1

0.972

MAPK13

0.970

MAPK12

0.968

MAPK3

0.964

CREB1

0.961

CREBBP

0.961

CREB5

0.957

ATF4

0.939

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ATF4	ENSLAFP00000005426	ENSLAFP00000010042	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Activating transcription factor 4.	0.939
ATF2	CREB1	ENSLAFP00000005426	ENSLAFP00000011090	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 1.	0.961
ATF2	CREB5	ENSLAFP00000005426	ENSLAFP00000025971	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.957
ATF2	CREBBP	ENSLAFP00000005426	ENSLAFP00000013091	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	CREB binding protein.	0.961
ATF2	JUN	ENSLAFP00000005426	ENSLAFP00000016280	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.989
ATF2	MAPK1	ENSLAFP00000005426	ENSLAFP00000008420	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.972
ATF2	MAPK12	ENSLAFP00000005426	ENSLAFP00000013931	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.968
ATF2	MAPK13	ENSLAFP00000005426	ENSLAFP00000004302	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.970
ATF2	MAPK14	ENSLAFP00000005426	ENSLAFP00000004298	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.990
ATF2	MAPK3	ENSLAFP00000005426	ENSLAFP00000029396	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.964
ATF4	ATF2	ENSLAFP00000010042	ENSLAFP00000005426	Activating transcription factor 4.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.939
ATF4	CREB1	ENSLAFP00000010042	ENSLAFP00000011090	Activating transcription factor 4.	cAMP responsive element binding protein 1.	0.927
ATF4	CREB5	ENSLAFP00000010042	ENSLAFP00000025971	Activating transcription factor 4.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.933
ATF4	CREBBP	ENSLAFP00000010042	ENSLAFP00000013091	Activating transcription factor 4.	CREB binding protein.	0.955
ATF4	JUN	ENSLAFP00000010042	ENSLAFP00000016280	Activating transcription factor 4.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.622
ATF4	MAPK1	ENSLAFP00000010042	ENSLAFP00000008420	Activating transcription factor 4.	Mitogen-activated protein kinase.	0.903
ATF4	MAPK3	ENSLAFP00000010042	ENSLAFP00000029396	Activating transcription factor 4.	Mitogen-activated protein kinase.	0.903
CREB1	ATF2	ENSLAFP00000011090	ENSLAFP00000005426	cAMP responsive element binding protein 1.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.961
CREB1	ATF4	ENSLAFP00000011090	ENSLAFP00000010042	cAMP responsive element binding protein 1.	Activating transcription factor 4.	0.927
CREB1	CREB5	ENSLAFP00000011090	ENSLAFP00000025971	cAMP responsive element binding protein 1.	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.	0.921

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