Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GTF2IRD1GTF2I repeat domain containing 1. (936 aa)    
Predicted Functional Partners:
CLIP2
CAP-Gly domain containing linker protein 2.
 
    
 0.727
NSUN5
NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.706
GDF10
Bone morphogenetic protein 3; Belongs to the TGF-beta family.
      
 0.632
PIAS2
Protein inhibitor of activated STAT 2.
    
 
 0.629
HDAC3
Hist_deacetyl domain-containing protein.
    
 
 0.598
SORCS1
Sortilin related VPS10 domain containing receptor 1.
    
 
 0.579
FKBP6
Peptidylprolyl isomerase.
      
 0.572
RFC2
Replication factor C subunit 2.
      
 0.569
FKBP10
Peptidylprolyl isomerase.
      
 0.565
TBL2
Transducin beta like 2.
      
 0.564
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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