Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIA1PTPRF interacting protein alpha 1. (1159 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 0.722
G3UF18_LOXAF
C2 domain-containing protein.
    
 0.718
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.692
PPFIA3
PTPRF interacting protein alpha 3.
   
  0.591
PTPRF
Protein tyrosine phosphatase receptor type F.
    
 0.577
PTPRS
Protein tyrosine phosphatase receptor type S.
    
 0.577
PTPRD
Protein tyrosine phosphatase receptor type D.
   
 0.574
MPP1
Membrane palmitoylated protein 1; Belongs to the MAGUK family.
    
 0.568
PTPRE
Receptor-type tyrosine-protein phosphatase.
    
 0.529
ERC2
Uncharacterized protein.
   
 
 0.509
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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