SCN7A protein (Loxodonta africana) - STRING interaction network

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SCN7A

Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1931 aa)

Predicted Functional Partners:

SCN1B

0.849

SCN4B

0.821

UNC79

0.798

SCN2B

0.772

SCN3B

0.653

SCN10A

0.649

CACNB1

0.608

GNAO1

0.596

CALHM1

0.594

GNG10

0.594

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNB1	SCN10A	ENSLAFP00000015286	ENSLAFP00000026473	Calcium voltage-gated channel auxiliary subunit beta 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.502
CACNB1	SCN7A	ENSLAFP00000015286	ENSLAFP00000005476	Calcium voltage-gated channel auxiliary subunit beta 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.608
CALHM1	SCN7A	ENSLAFP00000007052	ENSLAFP00000005476	Calcium homeostasis modulator 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.594
GNAO1	GNG10	ENSLAFP00000001933	ENSLAFP00000029250	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.951
GNAO1	SCN7A	ENSLAFP00000001933	ENSLAFP00000005476	G protein subunit alpha o1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.596
GNG10	GNAO1	ENSLAFP00000029250	ENSLAFP00000001933	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit alpha o1.	0.951
GNG10	SCN7A	ENSLAFP00000029250	ENSLAFP00000005476	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.594
SCN10A	CACNB1	ENSLAFP00000026473	ENSLAFP00000015286	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Calcium voltage-gated channel auxiliary subunit beta 1.	0.502
SCN10A	SCN1B	ENSLAFP00000026473	ENSLAFP00000022435	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium voltage-gated channel beta subunit 1.	0.884
SCN10A	SCN2B	ENSLAFP00000026473	ENSLAFP00000002193	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium voltage-gated channel beta subunit 2.	0.830
SCN10A	SCN3B	ENSLAFP00000026473	ENSLAFP00000000307	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium voltage-gated channel beta subunit 3.	0.804
SCN10A	SCN4B	ENSLAFP00000026473	ENSLAFP00000007731	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium voltage-gated channel beta subunit 4.	0.771
SCN10A	SCN7A	ENSLAFP00000026473	ENSLAFP00000005476	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.649
SCN10A	UNC79	ENSLAFP00000026473	ENSLAFP00000006644	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Unc-79 homolog, NALCN channel complex subunit.	0.798
SCN1B	SCN10A	ENSLAFP00000022435	ENSLAFP00000026473	Sodium voltage-gated channel beta subunit 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.884
SCN1B	SCN2B	ENSLAFP00000022435	ENSLAFP00000002193	Sodium voltage-gated channel beta subunit 1.	Sodium voltage-gated channel beta subunit 2.	0.991
SCN1B	SCN3B	ENSLAFP00000022435	ENSLAFP00000000307	Sodium voltage-gated channel beta subunit 1.	Sodium voltage-gated channel beta subunit 3.	0.651
SCN1B	SCN4B	ENSLAFP00000022435	ENSLAFP00000007731	Sodium voltage-gated channel beta subunit 1.	Sodium voltage-gated channel beta subunit 4.	0.989
SCN1B	SCN7A	ENSLAFP00000022435	ENSLAFP00000005476	Sodium voltage-gated channel beta subunit 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.849
SCN2B	SCN10A	ENSLAFP00000002193	ENSLAFP00000026473	Sodium voltage-gated channel beta subunit 2.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.830

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