STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)    
Predicted Functional Partners:
PAFAH1B3
Platelet activating factor acetylhydrolase 1b catalytic subunit 3.
    
 0.997
NDE1
NudE neurodevelopment protein 1.
    
 0.995
NDEL1
NudE neurodevelopment protein 1 like 1.
    
 0.993
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 0.992
NUDC
Nuclear distribution C, dynein complex regulator.
   
 0.992
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
   
 0.989
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
   
 0.980
G3SYJ3_LOXAF
Dynein light chain.
    
 0.977
CKAP5
Cytoskeleton associated protein 5.
    
 0.977
DCTN1
CAP-Gly domain-containing protein.
   
 0.963
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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