Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RYR2Ryanodine receptor 2. (4951 aa)    
Predicted Functional Partners:
ASPH
Aspartate beta-hydroxylase.
   
 
 0.966
RYR1
Ryanodine receptor 1.
   
  0.965
RYR3
Ryanodine receptor 3.
   
  0.962
CALML6
Calmodulin like 6.
    
 0.950
G3SZS8_LOXAF
Uncharacterized protein.
   
 0.949
G3TTP7_LOXAF
Uncharacterized protein.
   
 0.949
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.937
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.937
NOS1
Nitric oxide synthase 1.
   
 
 0.909
CACNA1F
Calcium voltage-gated channel subunit alpha1 F.
   
 0.902
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.