STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIM1SIM bHLH transcription factor 1. (766 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
 
 0.693
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
   
 
 0.693
FOXG1
Uncharacterized protein.
    
 
 0.521
OTP
Orthopedia homeobox.
   
 
 0.497
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.490
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.484
CRTAC1
Cartilage acidic protein 1.
      
 0.480
TMEM132E
Transmembrane protein 132E.
      
 0.480
GRM4
Glutamate metabotropic receptor 4.
      
 0.439
G3UJI9_LOXAF
Uncharacterized protein.
      
 0.430
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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