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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAR2AAR2 splicing factor. (384 aa)    
Predicted Functional Partners:
PRPF8
Pre-mRNA processing factor 8.
    
 
 0.992
EFTUD2
Elongation factor Tu GTP binding domain containing 2.
    
 
 0.955
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
    
 
 0.912
ECD
Ecdysoneless cell cycle regulator.
    
 
 0.901
TSSC4
Tumor suppressing subtransferable candidate 4.
    
 
 0.861
CD2BP2
CD2 cytoplasmic tail binding protein 2.
   
 
 0.824
DDX23
DEAD-box helicase 23.
    
 
 0.764
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
    
 
 0.710
EAPP
E2F associated phosphoprotein.
    
 
 0.684
EEF2
Eukaryotic translation elongation factor 2.
    
 
 0.669
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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