STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMD2Monocyte to macrophage differentiation associated 2. (246 aa)    
Predicted Functional Partners:
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.864
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.864
ADK
Adenosine kinase.
      
 0.590
SPO11
SPO11 initiator of meiotic double stranded breaks.
      
 0.587
ANO5
Anoctamin.
      
 0.529
PHF11
PHD finger protein 11.
      
 0.515
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
   
  
 0.491
TRAPPC2B
Trafficking protein particle complex 2B.
   
  
 0.417
GCFC2
GC-rich sequence DNA-binding factor 2.
      
 0.416
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.