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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAMK4Calcium/calmodulin dependent protein kinase IV. (419 aa)    
Predicted Functional Partners:
CREB1
cAMP responsive element binding protein 1.
    
 0.969
CALM3
Calmodulin 3; Belongs to the calmodulin family.
   
 0.956
CALML5
Calmodulin like 5.
   
 0.956
CALML3
Calmodulin like 3; Belongs to the calmodulin family.
   
 0.956
CAMK2A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
0.929
CALML4
Calmodulin like 4.
   
 0.928
CAMKK2
Calcium/calmodulin dependent protein kinase kinase 2.
  
 
0.927
CAMKK1
Calcium/calmodulin dependent protein kinase kinase 1.
  
 
0.926
ATF6B
Activating transcription factor 6 beta.
   
 
 0.914
HDAC5
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.911
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.