STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAIPTRAF interacting protein. (470 aa)    
Predicted Functional Partners:
LRR1
Leucine rich repeat protein 1.
   
 
 0.682
NEIL3
Nei like DNA glycosylase 3.
   
  
 0.606
FANCD2
FA complementation group D2.
   
 
 0.580
FBXO5
F-box protein 5.
   
  
 0.536
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 
 0.536
TATDN3
TatD DNase domain containing 3.
      
 0.525
SPRTN
SprT-like N-terminal domain.
      
 0.516
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 
 0.483
CDC45
Cell division cycle 45.
   
  
 0.473
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
      
 0.453
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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