Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LUMLumican. (340 aa)    
Predicted Functional Partners:
COL1A2
Collagen type I alpha 2 chain.
   
 0.987
COL3A1
Collagen type III alpha 1 chain.
   
 0.966
FBN1
Fibrillin 1.
   
 0.955
DCN
Decorin; May affect the rate of fibrils formation.
  
  
0.951
SPARC
Secreted protein acidic and cysteine rich.
   
 
 0.946
COL1A1
Collagen type I alpha 1 chain.
   
 0.943
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.893
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
     
  0.870
FASLG
Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family.
    
  0.870
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
    
 0.839
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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