STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (820 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.868
JUP
Junction plakoglobin.
   
 0.845
CTNND1
Catenin delta 1.
    
 0.786
ARVCF
ARVCF delta catenin family member.
    
 0.665
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
 0.635
MMP9
Matrix metallopeptidase 9.
    
 0.628
ADAM10
ADAM metallopeptidase domain 10.
     
 0.598
EGFR
Receptor protein-tyrosine kinase.
   
 
 0.577
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
    
 0.576
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
     
0.568
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.