STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (820 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.983
JUP
Junction plakoglobin.
   
 0.976
CTNND1
Catenin delta 1.
   
 0.973
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.927
CTNNA2
Uncharacterized protein.
   
 0.850
CTNNA2-2
Uncharacterized protein.
   
 0.850
CTNNA1
Catenin alpha 1.
   
 0.850
VCL
Vinculin.
   
 0.835
ARVCF
ARVCF delta catenin family member.
   
 0.822
ADAM10
ADAM metallopeptidase domain 10.
    
 0.820
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.