Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCKRGlucokinase regulator. (621 aa)    
Predicted Functional Partners:
GCK
Phosphotransferase.
   
 0.992
AMDHD2
N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
    
 0.832
HKDC1
Hexokinase domain containing 1.
   
 0.826
HK2
Hexokinase 2.
   
 0.826
HK1
Hexokinase 1.
   
 0.826
PGM3
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
     
 0.703
NUP107
Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).
     
 0.672
NUP85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
     
 0.667
NUP54
Nucleoporin 54.
     
 0.663
ZNF512
Zinc finger protein 512.
      
 0.645
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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