STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (176 aa)    
Predicted Functional Partners:
HSPA8
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.939
G3U506_LOXAF
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.939
HSPA1L
Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family.
   
 0.939
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA; Belongs to the small heat shock protein (HSP20) family.
  
 
0.805
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
   
 
 0.746
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
 
 0.724
HSPB6
Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family.
  
0.689
BAG3
BCL2 associated athanogene 3.
   
 
 0.683
HSPB2
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
  
 
0.676
HSF4
Heat shock transcription factor 4.
    
 0.661
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.