STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PITX3Paired like homeodomain 3. (255 aa)    
Predicted Functional Partners:
NR4A2
Nuclear receptor subfamily 4 group A member 2.
    
 
 0.725
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
      
 0.641
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.618
FOXE1
Forkhead box E1.
   
 
 0.592
PITX2
Homeobox protein.
   
   0.570
CRYBB2
Crystallin beta B2; Belongs to the beta/gamma-crystallin family.
      
 0.570
PITX1
Homeobox protein.
   
   0.570
CRYGS
Crystallin gamma S; Belongs to the beta/gamma-crystallin family.
      
 0.546
TH
Tyrosine hydroxylase.
    
 
 0.545
FOXA2
Forkhead box A2.
      
 0.542
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.