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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARFIP1ADP ribosylation factor interacting protein 1. (373 aa)    
Predicted Functional Partners:
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.837
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.697
SYNPO2
Synaptopodin 2.
    
 
 0.589
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
      
 0.554
RNF150
Ring finger protein 150.
   
  
 0.544
RAC2
Rac family small GTPase 2.
   
 0.535
RAC1
Rac family small GTPase 1.
   
 0.535
TMEM154
Transmembrane protein 154.
      
 0.527
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.526
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
      
 0.520
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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