Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTNNAL1Catenin alpha like 1. (730 aa)    
Predicted Functional Partners:
SNTB2
PH domain-containing protein.
    
 
 0.842
SNTG2
Syntrophin gamma 2.
   
 
 0.700
SNTG1
Syntrophin gamma 1.
   
 
 0.700
ADRA1B
Adrenoceptor alpha 1B.
    
 
 0.670
SNTB1
PDZ domain-containing protein.
    
 
 0.650
AFDN
Afadin, adherens junction formation factor.
   
 0.646
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.620
RNF135
Ring finger protein 135.
    
   0.594
TLN1
Talin 1.
   
 0.591
TLNRD1
Talin rod domain containing 1.
   
 0.591
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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