Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.577
KRT82
Keratin 82; Belongs to the intermediate filament family.
  
0.568
AK9
Uncharacterized protein.
    
 0.562
G3TCK5_LOXAF
Uncharacterized protein.
    
 0.562
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
 
 0.509
KRT77
Keratin 77; Belongs to the intermediate filament family.
  
0.481
ELOVL3
Elongation of very long chain fatty acids protein.
   
  
 0.474
KRT8
Keratin 8; Belongs to the intermediate filament family.
   
 0.469
DGAT2L6
Diacylglycerol O-acyltransferase 2 like 6.
     
 0.465
AWAT1
Acyl-CoA wax alcohol acyltransferase 1.
     
 0.462
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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