STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WNK2WNK lysine deficient protein kinase 2. (2184 aa)    
Predicted Functional Partners:
WNK1
WNK lysine deficient protein kinase 1.
   
 0.972
WNK3
WNK lysine deficient protein kinase 3.
   
 
 0.967
STK39
Serine/threonine kinase 39.
    
 0.910
OXSR1
Protein kinase domain-containing protein.
    
 0.910
CNTD1
Cyclin N-terminal domain containing 1.
   
 0.909
G3TKX7_LOXAF
Ion_trans domain-containing protein.
    
 0.875
SGK1
Non-specific serine/threonine protein kinase.
   
 0.865
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.817
KLHL3
Kelch like family member 3.
    
 
 0.612
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.596
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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