Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A45Solute carrier family 25 member 45; Belongs to the mitochondrial carrier (TC 2.A.29) family. (288 aa)    
Predicted Functional Partners:
ACSF2
Acyl-CoA synthetase family member 2.
   
 0.624
SLC5A9
Solute carrier family 5 member 9; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.624
SLC16A13
Solute carrier family 16 member 13.
   
  
 0.575
ARIH1
RBR-type E3 ubiquitin transferase.
      
 0.575
TPK1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
      
 0.575
FRMD8
FERM domain containing 8.
      
 0.552
FAM89B
Family with sequence similarity 89 member B.
      
 0.494
ZNRD2
Zinc ribbon domain containing 2.
      
 0.490
CDC42EP2
CDC42 effector protein 2.
      
 0.487
KCNK7
Potassium two pore domain channel subfamily K member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
  
 0.483
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]