Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP11Matrix metallopeptidase 11. (491 aa)    
Predicted Functional Partners:
SFRP4
Secreted frizzled related protein 4.
   
 
 0.954
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
    
 0.937
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.666
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.598
MMP13
Matrix metallopeptidase 13.
   
 0.571
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.555
SPP1
Secreted phosphoprotein 1.
   
 0.537
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
     
  0.521
MMP8
Matrix metallopeptidase 8.
   
 0.513
MMP9
Matrix metallopeptidase 9.
   
 0.511
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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