STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM53BFamily with sequence similarity 53 member B. (381 aa)    
Predicted Functional Partners:
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.718
SFN
Stratifin; Belongs to the 14-3-3 family.
    
 
 0.685
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
    
 
 0.664
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
    
 
 0.617
DCAF7
DDB1 and CUL4 associated factor 7.
    
 
 0.613
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
    
 
 0.594
CNIH2
Cornichon family AMPA receptor auxiliary protein 2.
      
 0.569
CNIH3
Cornichon family AMPA receptor auxiliary protein 3.
      
 0.569
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
      
 0.546
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.447
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.