STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)    
Predicted Functional Partners:
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.998
GTF2H1
General transcription factor IIH subunit 1.
   
 0.997
GTF2H3
General transcription factor IIH subunit 3.
    
 0.996
GTF2H2
General transcription factor IIH subunit.
    
 0.992
GTF2H5
General transcription factor IIH subunit 5.
    
 0.991
CCNH
Cyclin H; Belongs to the cyclin family.
    
 0.991
GTF2H4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.990
CDK7
Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.
    
 0.989
MNAT1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.987
XPA
XPA, DNA damage recognition and repair factor.
    
 0.981
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.