Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SSR4Signal sequence receptor subunit 4. (173 aa)    
Predicted Functional Partners:
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
 0.999
SSR3
Signal sequence receptor subunit 3.
   
 0.999
SSR1
Signal sequence receptor subunit 1.
   
 0.993
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.988
CAGE1
Cancer antigen 1.
   
 0.964
SEC61G
SEC61 translocon gamma subunit.
   
 0.925
KRTCAP2
Keratinocyte associated protein 2.
   
 
 0.896
RPL8
Ribosomal protein L8.
   
 
 0.894
SEC61A1
SEC61 translocon alpha 1 subunit.
   
 0.878
SEC61A2
SEC61 translocon alpha 2 subunit.
   
 0.878
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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