STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)    
Predicted Functional Partners:
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 0.993
LIN7A
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.973
APBA2
Amyloid beta precursor protein binding family A member 2.
   
 0.945
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.933
WHRN
Whirlin.
    
 0.918
CASKIN1
CASK interacting protein 1.
   
 0.917
APBA3
Amyloid beta precursor protein binding family A member 3.
   
 0.902
LIN7C
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.892
LIN7B
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 0.892
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 0.854
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.