close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND5ADENN domain containing 5A. (1252 aa)    
Predicted Functional Partners:
RAB6B
RAB6B, member RAS oncogene family.
    
 
 0.782
DENND4C
DENN domain containing 4C.
    
0.641
RAB28
RAB28, member RAS oncogene family.
     
 0.606
SNX1
Sorting nexin 1.
   
 
 0.567
SNX2
Sorting nexin 2.
   
 
 0.458
RAB6A
RAB6A, member RAS oncogene family.
    
 
 0.424
RAB7A
RAB7A, member RAS oncogene family.
     
 0.421
CHM
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.419
DENND1A
Uncharacterized protein.
    
 
 0.413
SLC35D2
TPT domain-containing protein.
 
      0.411
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (16%) [HD]