STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND5ADENN domain containing 5A. (1252 aa)    
Predicted Functional Partners:
DENND5B
DENN domain containing 5B.
   
   0.924
DENND4C
DENN domain containing 4C.
    
0.851
RAB6B
RAB6B, member RAS oncogene family.
    
 
 0.738
RAB28
RAB28, member RAS oncogene family.
     
 0.729
DENND3
DENN domain containing 3.
    
 
 0.709
DENND2B
Suppression of tumorigenicity 5.
    
 
 0.686
MADD
MAP kinase activating death domain.
    
 
 0.679
VPS26A
VPS26, retromer complex component A.
     
 0.611
SNX1
Sorting nexin 1.
     
 0.606
ZCCHC24
Zinc finger CCHC-type containing 24.
      
 0.595
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.