STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABL1Tyrosine-protein kinase. (1142 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
0.974
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.964
GRB2
Growth factor receptor bound protein 2.
   
0.963
CBL
Cbl proto-oncogene.
   
 0.952
RIN1
Ras and Rab interactor 1.
    
 0.950
ROBO1
Roundabout guidance receptor 1.
   
 0.944
RAC2
Rac family small GTPase 2.
   
 0.943
RB1
RB transcriptional corepressor 1.
    
 0.934
BCR
BCR activator of RhoGEF and GTPase.
    
 0.928
SHC1
SHC adaptor protein 1.
    
0.927
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.