STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
QRFPPyroglutamylated RFamide peptide. (136 aa)    
Predicted Functional Partners:
QRFPR
Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.972
OPN5
Opsin 5; Belongs to the G-protein coupled receptor 1 family.
    
 0.830
CCKBR
Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.820
CCKAR
Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family.
   
 0.819
GPR50
G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.
   
 0.772
GPR83
G protein-coupled receptor 83.
    
 0.754
PTGER3
Prostaglandin E receptor 3.
    
 0.722
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
      
 0.716
HCRT
Hypocretin neuropeptide precursor.
     
 0.640
DBH
Dopamine beta-hydroxylase.
   
  
 0.629
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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