STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QRFPPyroglutamylated RFamide peptide. (136 aa)    
Predicted Functional Partners:
QRFPR
Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.880
GPR83
G protein-coupled receptor 83.
     
 0.679
PTGER3
Prostaglandin E receptor 3.
     
 0.660
ADCYAP1
Adenylate cyclase activating polypeptide 1.
      
 0.624
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
   
 
 0.610
NPFFR1
Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.569
NPFFR2
Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.569
GPR135
G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.569
CCKBR
Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.561
CCKAR
Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.560
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.