Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL17RAInterleukin 17 receptor A. (852 aa)    
Predicted Functional Partners:
IL17A
Interleukin 17A.
    
 0.998
IL17F
Uncharacterized protein.
    
 0.992
IL25
Interleukin 25.
    
 0.991
IL17RC
Interleukin 17 receptor C.
    
0.989
TRAF3IP2
TRAF3 interacting protein 2.
    
 0.988
IL17RB
Interleukin 17 receptor B.
   
 0.985
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.966
IL17RE
Interleukin 17 receptor E.
    
 0.950
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.906
TNFAIP3
TNF alpha induced protein 3.
     
 0.879
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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