STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BSNDBarttin CLCNK type accessory beta subunit. (314 aa)    
Predicted Functional Partners:
LOC100654229
Chloride channel protein.
   
 
 0.972
PCSK7
Proprotein convertase subtilisin/kexin type 7.
      
 0.888
PCSK2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
      
 0.877
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
      
 0.869
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.776
PCSK9
Proprotein convertase subtilisin/kexin type 9.
      
 0.771
SLC12A1
Solute carrier family 12 member 1.
   
  
 0.763
LDLR
Low density lipoprotein receptor.
      
 0.759
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
      
 0.724
PCSK5
Proprotein convertase subtilisin/kexin type 5.
      
 0.718
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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