STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPN3Epsin 3. (643 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.981
G3U095_LOXAF
Uncharacterized protein.
    
 0.981
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.978
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 0.951
EPN1
Epsin 1.
    
 
0.913
ITSN1
Intersectin 1.
    
 0.842
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.817
EGFR
Receptor protein-tyrosine kinase.
    
 0.800
GAK
Cyclin G associated kinase.
   
 0.792
HIP1R
Huntingtin interacting protein 1 related.
    
 
 0.737
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.