STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRSepiapterin reductase. (267 aa)    
Predicted Functional Partners:
PAH
Phenylalanine hydroxylase.
   
 
 0.977
PTS
Uncharacterized protein.
  
 
 0.963
QDPR
Quinoid dihydropteridine reductase.
   
 0.954
DHFR
DHFR domain-containing protein.
     
 0.930
TPH2
Tryptophan hydroxylase 2.
   
 
 0.908
TH
Tyrosine hydroxylase.
   
 
 0.907
PRKG2
cGMP-dependent protein kinase.
   
 0.872
TPH1
BH4_AAA_HYDROXYL_2 domain-containing protein.
   
 
 0.853
G3UBE5_LOXAF
Uncharacterized protein.
   
 
 0.853
LOC100666118
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.837
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.