STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)    
Predicted Functional Partners:
UXS1
UDP-glucuronate decarboxylase 1.
 0.996
TGDS
TDP-glucose 4,6-dehydratase.
  
 
 0.974
GALE
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.947
GMPPB
GDP-mannose pyrophosphorylase B.
  
 
 0.942
GMPPA
GDP-mannose pyrophosphorylase A.
  
 
 0.930
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.922
UAP1
UDP-N-acetylglucosamine pyrophosphorylase 1.
   
 
 0.919
UAP1L1
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1.
   
 
 0.916
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
     
 0.887
CRYL1
Crystallin lambda 1.
     
 0.885
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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