UCP1 protein (Loxodonta africana) - STRING interaction network

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UCP1

Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)

Predicted Functional Partners:

NPY

0.615

ADRB3

0.587

PPARG

0.582

TH

0.544

CIDEA

0.514

TRPM8

0.510

TSHB

0.510

PCK1

0.504

SLC25A27

0.504

VWF

0.502

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB3	CIDEA	ENSLAFP00000026999	ENSLAFP00000002296	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Cell death inducing DFFA like effector a.	0.529
ADRB3	PPARG	ENSLAFP00000026999	ENSLAFP00000024076	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.490
ADRB3	UCP1	ENSLAFP00000026999	ENSLAFP00000005947	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.587
CIDEA	ADRB3	ENSLAFP00000002296	ENSLAFP00000026999	Cell death inducing DFFA like effector a.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.529
CIDEA	PPARG	ENSLAFP00000002296	ENSLAFP00000024076	Cell death inducing DFFA like effector a.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.641
CIDEA	UCP1	ENSLAFP00000002296	ENSLAFP00000005947	Cell death inducing DFFA like effector a.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.514
NPY	TH	ENSLAFP00000018092	ENSLAFP00000021655	Neuropeptide Y.	Tyrosine hydroxylase.	0.762
NPY	UCP1	ENSLAFP00000018092	ENSLAFP00000005947	Neuropeptide Y.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.615
PCK1	PPARG	ENSLAFP00000007767	ENSLAFP00000024076	Phosphoenolpyruvate carboxykinase 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.514
PCK1	UCP1	ENSLAFP00000007767	ENSLAFP00000005947	Phosphoenolpyruvate carboxykinase 1.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.504
PPARG	ADRB3	ENSLAFP00000024076	ENSLAFP00000026999	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.490
PPARG	CIDEA	ENSLAFP00000024076	ENSLAFP00000002296	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Cell death inducing DFFA like effector a.	0.641
PPARG	PCK1	ENSLAFP00000024076	ENSLAFP00000007767	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Phosphoenolpyruvate carboxykinase 1.	0.514
PPARG	TH	ENSLAFP00000024076	ENSLAFP00000021655	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Tyrosine hydroxylase.	0.416
PPARG	UCP1	ENSLAFP00000024076	ENSLAFP00000005947	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.582
SLC25A27	UCP1	ENSLAFP00000017959	ENSLAFP00000005947	Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.504
TH	NPY	ENSLAFP00000021655	ENSLAFP00000018092	Tyrosine hydroxylase.	Neuropeptide Y.	0.762
TH	PPARG	ENSLAFP00000021655	ENSLAFP00000024076	Tyrosine hydroxylase.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.416
TH	UCP1	ENSLAFP00000021655	ENSLAFP00000005947	Tyrosine hydroxylase.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.544
TRPM8	UCP1	ENSLAFP00000013003	ENSLAFP00000005947	Transient receptor potential cation channel subfamily M member 8.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.510

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