STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SDR42E1Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (372 aa)    
Predicted Functional Partners:
HSD17B2
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.803
ANTKMT
Adenine nucleotide translocase lysine methyltransferase.
    
 0.757
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.751
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.741
PEX11G
Peroxisomal biogenesis factor 11 gamma.
   
  
 0.740
CYP7B1
Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 0.734
SQLE
Squalene epoxidase.
   
 
 0.723
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.723
NCAPD2
Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
      
 0.722
WASHC1
WASH complex subunit 1.
      
 0.720
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.