Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTCFCCCTC-binding factor. (727 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.774
RAD21
RAD21 cohesin complex component.
   
 0.728
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.716
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.711
WRAP53
WD repeat containing antisense to TP53.
     
 0.620
SMC1A
Structural maintenance of chromosomes protein.
   
 0.615
STAG1
Stromal antigen 1.
   
 0.613
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.613
STAT1
Signal transducer and activator of transcription.
    
 0.593
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.592
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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