STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAN2A2Alpha-mannosidase. (1154 aa)    
Predicted Functional Partners:
MAN2A1
Alpha-mann_mid domain-containing protein.
  
  
 
0.945
FUT8
Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family.
    
 0.938
MGAT2
Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
     
 0.934
MGAT1
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase.
     
 0.934
UNC79
Unc-79 homolog, NALCN channel complex subunit.
      
 0.723
MAN1C1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.628
MAN1A1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.618
MAN1A2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.573
DPAGT1
Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1.
      
 0.524
COPB2
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 
    
 0.524
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.