UNC45A protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UNC45A

Unc-45 myosin chaperone A. (945 aa)

Predicted Functional Partners:

HSP90AB1

0.591

HSP90AA1

0.591

G3ULS6_LOXAF

0.591

HSP90B1

0.536

MYO1E

0.534

MYO1F

0.534

TSC1

0.529

TRAP1

0.529

SMYD1

0.485

MYO5A

0.443

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3ULS6_LOXAF	UNC45A	ENSLAFP00000028785	ENSLAFP00000005984	Uncharacterized protein.	Unc-45 myosin chaperone A.	0.591
HSP90AA1	HSP90AB1	ENSLAFP00000025294	ENSLAFP00000019545	HATPase_c domain-containing protein.	Heat shock protein 90 alpha family class B member 1.	0.900
HSP90AA1	HSP90B1	ENSLAFP00000025294	ENSLAFP00000013455	HATPase_c domain-containing protein.	Heat shock protein 90 beta family member 1.	0.927
HSP90AA1	UNC45A	ENSLAFP00000025294	ENSLAFP00000005984	HATPase_c domain-containing protein.	Unc-45 myosin chaperone A.	0.591
HSP90AB1	HSP90AA1	ENSLAFP00000019545	ENSLAFP00000025294	Heat shock protein 90 alpha family class B member 1.	HATPase_c domain-containing protein.	0.900
HSP90AB1	HSP90B1	ENSLAFP00000019545	ENSLAFP00000013455	Heat shock protein 90 alpha family class B member 1.	Heat shock protein 90 beta family member 1.	0.927
HSP90AB1	UNC45A	ENSLAFP00000019545	ENSLAFP00000005984	Heat shock protein 90 alpha family class B member 1.	Unc-45 myosin chaperone A.	0.591
HSP90B1	HSP90AA1	ENSLAFP00000013455	ENSLAFP00000025294	Heat shock protein 90 beta family member 1.	HATPase_c domain-containing protein.	0.927
HSP90B1	HSP90AB1	ENSLAFP00000013455	ENSLAFP00000019545	Heat shock protein 90 beta family member 1.	Heat shock protein 90 alpha family class B member 1.	0.927
HSP90B1	UNC45A	ENSLAFP00000013455	ENSLAFP00000005984	Heat shock protein 90 beta family member 1.	Unc-45 myosin chaperone A.	0.536
MYO1E	UNC45A	ENSLAFP00000004043	ENSLAFP00000005984	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Unc-45 myosin chaperone A.	0.534
MYO1F	UNC45A	ENSLAFP00000009575	ENSLAFP00000005984	Myosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Unc-45 myosin chaperone A.	0.534
MYO5A	UNC45A	ENSLAFP00000000636	ENSLAFP00000005984	Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Unc-45 myosin chaperone A.	0.443
SMYD1	UNC45A	ENSLAFP00000006602	ENSLAFP00000005984	SET and MYND domain containing 1.	Unc-45 myosin chaperone A.	0.485
TRAP1	UNC45A	ENSLAFP00000024119	ENSLAFP00000005984	TNF receptor associated protein 1.	Unc-45 myosin chaperone A.	0.529
TSC1	UNC45A	ENSLAFP00000007076	ENSLAFP00000005984	TSC complex subunit 1.	Unc-45 myosin chaperone A.	0.529
UNC45A	G3ULS6_LOXAF	ENSLAFP00000005984	ENSLAFP00000028785	Unc-45 myosin chaperone A.	Uncharacterized protein.	0.591
UNC45A	HSP90AA1	ENSLAFP00000005984	ENSLAFP00000025294	Unc-45 myosin chaperone A.	HATPase_c domain-containing protein.	0.591
UNC45A	HSP90AB1	ENSLAFP00000005984	ENSLAFP00000019545	Unc-45 myosin chaperone A.	Heat shock protein 90 alpha family class B member 1.	0.591
UNC45A	HSP90B1	ENSLAFP00000005984	ENSLAFP00000013455	Unc-45 myosin chaperone A.	Heat shock protein 90 beta family member 1.	0.536

page 1 of 2

Server load: low (32%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About