Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDZD2PDZ domain containing 2. (2624 aa)    
Predicted Functional Partners:
G3UDB7_LOXAF
PDZ domain-containing protein.
 
      0.899
SUOX
Sulfite oxidase.
     
  0.790
PIM3
Protein kinase domain-containing protein.
    
 
 0.588
CTNND2
Catenin delta 2.
    
 
 0.572
PKP4
Plakophilin 4.
    
 
 0.572
VGLL4
Vestigial like family member 4.
      
 0.492
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.489
CLDN12
Claudin 12.
  
  
  0.485
DHX35
DEAH-box helicase 35.
    
 0.453
IFT57
Intraflagellar transport 57.
    
 0.448
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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