Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCAMMelanoma cell adhesion molecule. (644 aa)    
Predicted Functional Partners:
PECAM1
Platelet and endothelial cell adhesion molecule 1.
   
 0.614
AFDN
Afadin, adherens junction formation factor.
    
 0.597
ENG
Endoglin.
   
  
 0.579
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
     
 0.538
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
   
  
 0.505
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 
 0.502
THY1
Thy-1 cell surface antigen.
      
 0.502
CD34
CD34 molecule.
      
 0.487
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.479
EXOC3L4
Exocyst complex component 3 like 4.
  
     0.459
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.