Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GPBP1GC-rich promoter binding protein 1. (493 aa)    
Predicted Functional Partners:
FNDC11
Fibronectin type III domain containing 11.
    
   0.793
NNT
Nicotinamide nucleotide transhydrogenase.
      
 0.551
PSMC1
Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.
      
 0.547
CNOT2
CCR4-NOT transcription complex subunit 2.
   
 
 0.500
VBP1
Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.
      
 0.500
EAPP
E2F associated phosphoprotein.
      
 0.492
ND2
NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
      
 0.491
ZZZ3
Uncharacterized protein.
   
  
 0.490
DRG2
Developmentally regulated GTP binding protein 2.
      
 0.485
SH3D19
SH3 domain containing 19.
      
 0.465
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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