MVD protein (Loxodonta africana) - STRING interaction network

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MVD

Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (398 aa)

Predicted Functional Partners:

MVK

0.988

PMVK

0.964

IDI1

0.953

IDI2

0.953

RUSC1

0.952

GGPS1

0.947

HMGCS1

0.894

NSDHL

0.870

C16orf58

0.853

FBXO30

0.820

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C16orf58	MVD	ENSLAFP00000004812	ENSLAFP00000006051	Chromosome 16 open reading frame 58.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.853
FBXO30	GGPS1	ENSLAFP00000016292	ENSLAFP00000010060	F-box protein 30.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.803
FBXO30	HMGCS1	ENSLAFP00000016292	ENSLAFP00000015076	F-box protein 30.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.649
FBXO30	IDI1	ENSLAFP00000016292	ENSLAFP00000003104	F-box protein 30.	Isopentenyl-diphosphate delta isomerase 1.	0.730
FBXO30	IDI2	ENSLAFP00000016292	ENSLAFP00000005209	F-box protein 30.	Isopentenyl-diphosphate delta isomerase 2.	0.730
FBXO30	MVD	ENSLAFP00000016292	ENSLAFP00000006051	F-box protein 30.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.820
FBXO30	MVK	ENSLAFP00000016292	ENSLAFP00000028737	F-box protein 30.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.466
FBXO30	PMVK	ENSLAFP00000016292	ENSLAFP00000008279	F-box protein 30.	Phosphomevalonate kinase.	0.421
GGPS1	FBXO30	ENSLAFP00000010060	ENSLAFP00000016292	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	F-box protein 30.	0.803
GGPS1	HMGCS1	ENSLAFP00000010060	ENSLAFP00000015076	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.616
GGPS1	IDI1	ENSLAFP00000010060	ENSLAFP00000003104	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	Isopentenyl-diphosphate delta isomerase 1.	0.911
GGPS1	IDI2	ENSLAFP00000010060	ENSLAFP00000005209	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	Isopentenyl-diphosphate delta isomerase 2.	0.875
GGPS1	MVD	ENSLAFP00000010060	ENSLAFP00000006051	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.947
GGPS1	MVK	ENSLAFP00000010060	ENSLAFP00000028737	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.571
GGPS1	NSDHL	ENSLAFP00000010060	ENSLAFP00000012083	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.	0.492
GGPS1	PMVK	ENSLAFP00000010060	ENSLAFP00000008279	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	Phosphomevalonate kinase.	0.531
GGPS1	RUSC1	ENSLAFP00000010060	ENSLAFP00000025390	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	RUN and SH3 domain containing 1.	0.940
HMGCS1	FBXO30	ENSLAFP00000015076	ENSLAFP00000016292	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	F-box protein 30.	0.649
HMGCS1	GGPS1	ENSLAFP00000015076	ENSLAFP00000010060	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.616
HMGCS1	IDI1	ENSLAFP00000015076	ENSLAFP00000003104	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Isopentenyl-diphosphate delta isomerase 1.	0.912

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