Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SF1Splicing factor 1. (645 aa)    
Predicted Functional Partners:
PRPF40A
Pre-mRNA processing factor 40 homolog A.
   
 0.926
SF3A2
Splicing factor 3a subunit 2.
   
 0.918
DDX17
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 0.917
U2AF2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.912
G3TV31_LOXAF
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.912
DDX5
DEAD-box helicase 5; Belongs to the DEAD box helicase family.
   
 0.908
SUGP1
SURP and G-patch domain containing 1.
   
 0.908
DDX46
DEAD-box helicase 46.
   
 0.902
SF3B1
Splicing factor 3b subunit 1.
   
 0.898
RBM23
RNA binding motif protein 23.
   
 0.889
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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