Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC22A16Solute carrier family 22 member 16. (522 aa)    
Predicted Functional Partners:
YJEFN3
YjeF N-terminal domain-containing protein.
    
   0.687
NDUFA13
NADH:ubiquinone oxidoreductase subunit A13.
    
   0.687
SMOX
Spermine oxidase.
     
 0.672
AZIN1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 
 0.662
AGBL4
Peptidase_M14 domain-containing protein.
      
 0.623
SLC25A16
Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.618
SLC22A18
Solute carrier family 22 member 18.
   
 0.597
SLC44A4
Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family.
   
 
 0.568
DDO
D-aspartate oxidase.
 
 
 
 0.524
AMD1
S-adenosylmethionine decarboxylase proenzyme.
    
 
 0.517
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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