Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR86WD_REPEATS_REGION domain-containing protein. (361 aa)    
Predicted Functional Partners:
TXNDC9
Thioredoxin domain containing 9.
    
   0.804
SKOR2
SKI family transcriptional corepressor 2.
      
 0.737
CCT5
Chaperonin containing TCP1 subunit 5.
    
  0.699
RBX1
Ring-box 1.
    
 0.678
CDC6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
    
 0.677
PDCL
Phosducin like.
    
 
 0.669
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.631
PKP3
Plakophilin 3.
    
 
 0.631
CCT3
T-complex protein 1 subunit gamma.
   
  0.624
CCT7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
  0.597
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (10%) [HD]