STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRXCone-rod homeobox. (299 aa)    
Predicted Functional Partners:
NRL
Neural retina leucine zipper.
    
 
 0.716
CPLX4
Complexin 4.
   
  
 0.652
LCAT
Lecithin-cholesterol acyltransferase.
      
 0.622
INSR
Tyrosine-protein kinase receptor.
      
 0.599
NR2E3
Nuclear receptor subfamily 2 group E member 3.
   
 
 0.595
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
   
 
 0.586
CABP5
Calcium binding protein 5.
   
  
 0.583
CREB3L1
cAMP responsive element binding protein 3 like 1.
      
 0.567
OPN1SW
Opsin 1, short wave sensitive.
   
  
 0.551
RCVRN
Recoverin.
   
  
 0.546
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.