STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRXCone-rod homeobox. (299 aa)    
Predicted Functional Partners:
NRL
Neural retina leucine zipper.
    
 
 0.740
CPLX4
Complexin 4.
   
  
 0.642
CABP5
Calcium binding protein 5.
   
  
 0.556
OPN1SW
Opsin 1, short wave sensitive.
   
  
 0.498
ZNF366
Zinc finger protein 366.
    
 
 0.474
NR2E3
Nuclear receptor subfamily 2 group E member 3.
   
 
 0.465
G3TTN3_LOXAF
Uncharacterized protein.
      
 0.459
ELSPBP1
Epididymal sperm binding protein 1.
      
 0.454
POU5F1
POU domain protein.
   
 
 0.452
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
   
  
 0.437
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.