Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (375 aa)    
Predicted Functional Partners:
GNAI1
G protein subunit alpha i1.
    
 0.911
GNA13
G protein subunit alpha 13.
    
 0.904
GNA12
G protein subunit alpha 12.
    
 0.904
S1PR4
Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
 0.880
S1PR2
Sphingosine-1-phosphate receptor 2.
     
 0.873
HBEGF
Heparin binding EGF like growth factor.
     
 0.872
GNAI2
G protein subunit alpha i2.
    
 0.857
GNAI3
G protein subunit alpha i3.
    
 0.857
S1PR5
Sphingosine-1-phosphate receptor 5.
     
 0.828
GNAQ
G protein subunit alpha q.
    
 0.800
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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