STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VCPValosin containing protein; Belongs to the AAA ATPase family. (802 aa)    
Predicted Functional Partners:
NPLOC4
NPL4 homolog, ubiquitin recognition factor.
   
 0.998
NSFL1C
NSFL1 cofactor.
   
 0.997
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.995
UBXN4
UBX domain protein 4.
   
 0.995
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
   
 0.995
UBXN1
UBX domain protein 1.
   
 0.994
UBXN6
UBX domain protein 6.
    
 0.994
UBXN8
UBX domain protein 8.
   
 0.992
UBXN2A
UBX domain protein 2A.
   
 0.992
UBXN7
UBX domain-containing protein 7.
   
 0.992
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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